Casual wear is widely acceptable, but Djibouti is a Muslim country and certain codes of behaviour should be observed. Shorts are generally not appropriate outside of hotels, beaches or sport activities.
Health insurance is advisable. Doctors and hospitals may expect immediate cash payment for any medical treatment. A yellow fever vaccination certificate is required for visitors over one year of age coming from infected areas.
Cholera is also a serious risk and precautions are essential. Up-to-date advice should be sought before deciding if these precautions should include vaccination as medical opinion is divided over its effectiveness. Typhoid immunization is usually advised.